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Stomach Acid

Best Betaine Supplements (TMG) for Digestion, Heart Health, and Athletic Performance

Betaine supplements have gained significant attention in recent years for their diverse health benefits, but confusion often arises because “betaine” actually refers to two distinct supplement forms with very different uses. Betaine hydrochloride (betaine HCl) supports digestive function by increasing stomach acid, while trimethylglycine (TMG, also called betaine anhydrous) acts as a methyl donor supporting cardiovascular health, athletic performance, and cellular metabolism. Understanding which form of betaine you need—and why—is critical for achieving your health goals. This comprehensive guide examines the science behind both forms of betaine, their unique benefits, proper dosing strategies, and the best supplement products available today.