Muscle

For decades, creatine has been dismissed as a supplement “for men” or “for bodybuilders.” That narrative is changing rapidly. Research from 2025 and 2026 reveals that women may benefit from creatine in ways men don’t—particularly for brain health, mood regulation, menopause support, and cognitive function during hormonal fluctuations. Women have 70-80% lower endogenous creatine stores compared to men, making supplementation potentially more impactful. Yet many women avoid creatine due to myths about weight gain, bloating, or masculinization. This comprehensive guide examines what the research actually shows about creatine for women across the lifespan—from menstruation through pregnancy to menopause.