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Calorie Deficit

HMB vs Leucine for Muscle Retention During Cutting Phase

Quick Answer: HMB for Aggressive Cuts, Leucine for Moderate Deficits # Winner depends on cutting severity and protein intake: HMB (beta-hydroxy-beta-methylbutyrate) wins for: Aggressive calorie deficits (>500-750 cal/day below maintenance) Low-moderate protein intakes (<2.0g/kg bodyweight) Rapid fat loss phases (contest prep, photoshoot deadlines) Fasted cardio or training in glycogen-depleted states Elderly individuals (higher muscle loss risk during dieting) Research support (12-week study, 750 cal deficit):