AMH

Anti-Müllerian hormone (AMH) has become the gold-standard biomarker for ovarian reserve—the number of eggs remaining in your ovaries. Low AMH is often delivered as devastating news to women trying to conceive, implying a rapidly closing fertility window. But what does low AMH actually mean, can you raise it naturally, and does increasing AMH even matter for fertility outcomes? The biology is nuanced. AMH is secreted by granulosa cells in small antral follicles (2-8mm), reflecting the population of resting follicles potentially available for recruitment each cycle. Higher AMH = more follicles in reserve. Lower AMH = fewer follicles remaining. Since women are born with all the eggs they’ll ever have (approximately 1-2 million at birth, declining to 300,000-500,000 by puberty and ~25,000 by age 37), AMH declines steadily with age. The rate of decline accelerates after 35.