GLP-1 Drugs and PCOS: Can Ozempic Help Women with PCOS Lose Weight and Regulate Cycles?
GLP-1 Drugs and PCOS: Can Ozempic Help Women with PCOS Lose Weight and Regulate Cycles? # Polycystic ovary syndrome (PCOS) affects 8-13% of reproductive-aged women and is the leading cause of female infertility worldwide.[1] The hallmark features—insulin resistance, obesity, irregular menstrual cycles, hyperandrogenism, and metabolic dysfunction—create a self-reinforcing cycle that traditional treatments struggle to break. GLP-1 receptor agonists like Ozempic (semaglutide), Mounjaro (tirzepatide), and Wegovy represent a paradigm shift in PCOS management, addressing the underlying metabolic dysfunction while producing significant weight loss. This comprehensive guide examines the clinical evidence, mechanisms, practical protocols, and fertility considerations for using GLP-1 medications in women with PCOS.